What we offer

Southern RNA offers a comprehensive analytical platform for nucleic acid product, combined with the knowledge and experience of our team of talented scientists.

Analysis of plasmid DNA, mRNA CDMO, cap analogs, etc.
Assay/Method development, qualification, validation, and verification
Support with design and implementation of stability studies on nucleic acid products
Suite of qualified and calibrated analytical equipment for rapid bioburden/sterility testing, UV-Vis spectrophotometry, endotoxin testing, sanger sequencing, microscopy, microbiological analysis, compendial testing, chromatography, etc.

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You can count on us for

Strong technical capabilities and expertise for analytical testing, review, and release of critical raw materials and finished products with detailed certificate of analysis supplied
Quality management system with good documentation practices implemented with CAPA and deviation handling procedures in place

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Analytical panel for testing and stability studies

We develop cutting-edge Process Analytics Technologies (PAT) and offer quality control testing to support high-quality manufacturing of pDNA and mRNA services.

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Assay	pDNA	mRNA
Product Appearance
Sequence Identity
Bioburden Testing
Conductivity Analysis(USP <644>)
pH Analysis (USP<791>)
Endotoxin
Sterility Testing (USP <71>)
Purity (HPLC)
Identification by AGE
Identification by CGE
Purity (AGE)
Purity (UV spec.)
Quantitation of Residual Protein
Poly-A tail length Analysis
Restriction Endonuclease Analysis
DNA Homogeneity (AGE)
DNA Homogeneity (HPLC)
Quantitation of Residual Antibiotics
Quantitation of Residual Host Genomic DNA
Quantitation of Residual Host RNA
Capping Efficiency Analysis (HPLC)
Quantitation of Residual dsRNA
Quantitation of Residual pDNA